zinc protamine insulin - определение. Что такое zinc protamine insulin
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Что (кто) такое zinc protamine insulin - определение

PHARMACEUTICAL DRUG
Insulin, isophane; Actraphane; Protophane; Neutral protamine Hagedorn; Humulin N; Novolin N; Insulatard; Protamine insulin; Isophane insulin; Protamine zinc insulin; Insulin NPH; Protaphane; Human isophane insulin; Insulin isophane

insulin         
  • Charles Best]] in 1924
  • Charles Best]] and Clark Noble ca. 1920
  • Chart for Elizabeth Hughes, used to track blood, urine, diet in grams, and dietary prescriptions in grams
  • Diagram of insulin regulation upon high blood glucose
  • '''Effect of insulin on glucose uptake and metabolism.''' Insulin binds to its receptor (1), which starts many protein activation cascades (2). These include translocation of Glut-4 transporter to the [[plasma membrane]] and influx of glucose (3), [[glycogen]] synthesis (4), [[glycolysis]] (5) and triglyceride synthesis (6).
  • Insulin undergoes extensive posttranslational modification along the production pathway. Production and secretion are largely independent; prepared insulin is stored awaiting secretion. Both C-peptide and mature insulin are biologically active. Cell components and proteins in this image are not to scale.
  • Two vials of insulin. They have been given trade names, Actrapid (left) and NovoRapid (right) by the manufacturers.
  • [[Nicolae Paulescu]]
  • Insulin release from pancreas oscillates with a period of 3–6&nbsp;minutes.<ref name="hellman" />
  • The insulin signal transduction pathway begins when insulin binds to the insulin receptor proteins. Once the transduction pathway is completed, the GLUT-4 storage vesicles becomes one with the cellular membrane. As a result, the GLUT-4 protein channels become embedded into the membrane, allowing glucose to be transported into the cell.
  • sugar]]-rich versus a [[starch]]-rich meal is highlighted.
PANCREAS HORMONE
Insulin purified pork; Insulin recombinant human; Insulin recombinant purified human; Insulin pork; Insulin purified beef; Insulin glargine recombinant; Insulin zinc susp extended purified beef; Insulin zinc susp extended recombinant human; Insulin zinc susp prompt beef; Insulin zinc susp prompt purified pork; Insulin zinc susp extended beef; Insulin zinc susp purified beef; Insulin zinc susp purified pork; Insulin zinc susp recombinant human; Insulin zinc susp semisynthetic purified human; Iletin i (beef-pork); Insulin antagonists; Oral insulin; C257H383N65O77S6; Human Mixtard; Human mixtard; Preproinsulin; Insulin release; Insulin gene; Pre-proinsulin; C65R; B10H; Insullin; Insuline; Aktrapid; Iletin II; Insulin, porcine; INS (gene); Draft:Regulation of the insulin gene; Biosynthesis of insulin; Evolution of insulin
Insulin is a substance that most people produce naturally in their body and which controls the level of sugar in their blood.
In diabetes the body produces insufficient insulin.
N-UNCOUNT
insulin         
  • Charles Best]] in 1924
  • Charles Best]] and Clark Noble ca. 1920
  • Chart for Elizabeth Hughes, used to track blood, urine, diet in grams, and dietary prescriptions in grams
  • Diagram of insulin regulation upon high blood glucose
  • '''Effect of insulin on glucose uptake and metabolism.''' Insulin binds to its receptor (1), which starts many protein activation cascades (2). These include translocation of Glut-4 transporter to the [[plasma membrane]] and influx of glucose (3), [[glycogen]] synthesis (4), [[glycolysis]] (5) and triglyceride synthesis (6).
  • Insulin undergoes extensive posttranslational modification along the production pathway. Production and secretion are largely independent; prepared insulin is stored awaiting secretion. Both C-peptide and mature insulin are biologically active. Cell components and proteins in this image are not to scale.
  • Two vials of insulin. They have been given trade names, Actrapid (left) and NovoRapid (right) by the manufacturers.
  • [[Nicolae Paulescu]]
  • Insulin release from pancreas oscillates with a period of 3–6&nbsp;minutes.<ref name="hellman" />
  • The insulin signal transduction pathway begins when insulin binds to the insulin receptor proteins. Once the transduction pathway is completed, the GLUT-4 storage vesicles becomes one with the cellular membrane. As a result, the GLUT-4 protein channels become embedded into the membrane, allowing glucose to be transported into the cell.
  • sugar]]-rich versus a [[starch]]-rich meal is highlighted.
PANCREAS HORMONE
Insulin purified pork; Insulin recombinant human; Insulin recombinant purified human; Insulin pork; Insulin purified beef; Insulin glargine recombinant; Insulin zinc susp extended purified beef; Insulin zinc susp extended recombinant human; Insulin zinc susp prompt beef; Insulin zinc susp prompt purified pork; Insulin zinc susp extended beef; Insulin zinc susp purified beef; Insulin zinc susp purified pork; Insulin zinc susp recombinant human; Insulin zinc susp semisynthetic purified human; Iletin i (beef-pork); Insulin antagonists; Oral insulin; C257H383N65O77S6; Human Mixtard; Human mixtard; Preproinsulin; Insulin release; Insulin gene; Pre-proinsulin; C65R; B10H; Insullin; Insuline; Aktrapid; Iletin II; Insulin, porcine; INS (gene); Draft:Regulation of the insulin gene; Biosynthesis of insulin; Evolution of insulin
¦ noun Biochemistry a polypeptide pancreatic hormone which lowers glucose levels in the blood, a lack of which causes diabetes.
Origin
early 20th cent.: from L. insula 'island' (with ref. to the islets of Langerhans in the pancreas) + -in1.
Insulin         
  • Charles Best]] in 1924
  • Charles Best]] and Clark Noble ca. 1920
  • Chart for Elizabeth Hughes, used to track blood, urine, diet in grams, and dietary prescriptions in grams
  • Diagram of insulin regulation upon high blood glucose
  • '''Effect of insulin on glucose uptake and metabolism.''' Insulin binds to its receptor (1), which starts many protein activation cascades (2). These include translocation of Glut-4 transporter to the [[plasma membrane]] and influx of glucose (3), [[glycogen]] synthesis (4), [[glycolysis]] (5) and triglyceride synthesis (6).
  • Insulin undergoes extensive posttranslational modification along the production pathway. Production and secretion are largely independent; prepared insulin is stored awaiting secretion. Both C-peptide and mature insulin are biologically active. Cell components and proteins in this image are not to scale.
  • Two vials of insulin. They have been given trade names, Actrapid (left) and NovoRapid (right) by the manufacturers.
  • [[Nicolae Paulescu]]
  • Insulin release from pancreas oscillates with a period of 3–6&nbsp;minutes.<ref name="hellman" />
  • The insulin signal transduction pathway begins when insulin binds to the insulin receptor proteins. Once the transduction pathway is completed, the GLUT-4 storage vesicles becomes one with the cellular membrane. As a result, the GLUT-4 protein channels become embedded into the membrane, allowing glucose to be transported into the cell.
  • sugar]]-rich versus a [[starch]]-rich meal is highlighted.
PANCREAS HORMONE
Insulin purified pork; Insulin recombinant human; Insulin recombinant purified human; Insulin pork; Insulin purified beef; Insulin glargine recombinant; Insulin zinc susp extended purified beef; Insulin zinc susp extended recombinant human; Insulin zinc susp prompt beef; Insulin zinc susp prompt purified pork; Insulin zinc susp extended beef; Insulin zinc susp purified beef; Insulin zinc susp purified pork; Insulin zinc susp recombinant human; Insulin zinc susp semisynthetic purified human; Iletin i (beef-pork); Insulin antagonists; Oral insulin; C257H383N65O77S6; Human Mixtard; Human mixtard; Preproinsulin; Insulin release; Insulin gene; Pre-proinsulin; C65R; B10H; Insullin; Insuline; Aktrapid; Iletin II; Insulin, porcine; INS (gene); Draft:Regulation of the insulin gene; Biosynthesis of insulin; Evolution of insulin
Insulin (, from Latin insula, 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the INS gene. It is considered to be the main anabolic hormone of the body.

Википедия

NPH insulin

Neutral Protamine Hagedorn (NPH) insulin, also known as isophane insulin, is an intermediate-acting insulin given to help control blood sugar levels in people with diabetes. It is used by injection under the skin once to twice a day. Onset of effects is typically in 90 minutes and they last for 24 hours. Versions are available that come premixed with a short-acting insulin, such as regular insulin.

The common side effect is low blood sugar. Other side effects may include pain or skin changes at the sites of injection, low blood potassium, and allergic reactions. Use during pregnancy is relatively safe for the baby. NPH insulin is made by mixing regular insulin and protamine in exact proportions with zinc and phenol such that a neutral-pH is maintained and crystals form. There are human and pig insulin based versions.

Protamine insulin was first created in 1936 and NPH insulin in 1946. It is on the World Health Organization's List of Essential Medicines. NPH is an abbreviation for "neutral protamine Hagedorn". In 2020, insulin isophane was the 221st most commonly prescribed medication in the United States, with more than 2 million prescriptions. In 2020, the combination of human insulin with insulin isophane was the 246th most commonly prescribed medication in the United States, with more than 1 million prescriptions.